Insights in Pediatric Cardiology

The association between the environmental endocrine disruptors and Cardiovascular diseases: a systematic review and meta-analysis

Backgroundï¼Ãƒâ€šÃ‚Å¡Except for known cardiovascular risk factors, long-term exposure to environmental Endocrine disruptors (EEDs) has been proved to increase the risk of cardiovascular diseases (CVD), which are still controversial. Objective: The aim of the study was to evaluate the relationship between CVD and EEDs which are most closely related to daily life .comprehensively explore the associations between EEDs exposure and CVDfor the first time. Besides,. In addition, gender, age, body mass index (BMI), waist circumference (WC), total cholesterol (TC), high density lipoprotein (HDL), and low-density lipoprotein (LDL) were analysed in subgroup for the first time. To explore the role of these specific variables in the impact of BPA on CVD risk. Methods: The heterogeneity between different studies was qualitatively and quantitatively evaluated using Q test and I2 statistical magnitude, respectively in Stata12.0 software. Subgroup analysis was performed using chemical homologs, a previously unused grouping method, to extract data and perform meta-analysis to assess their exposure to CVD.

Xiangjun Fu