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Cardiac biomarkers in a select cohort of Pediatric heart disease: Galectin-3,hsCRP and NT-proBNP

Patients with single ventricle physiology are the most vulnerable patients with congenital heart defects (CHD) requiring up to three cardiac surgical palliations to survive into adulthood. Long term survival of these patients is dependent upon excellent surgical intervention and outcomes, long term follow-up and prediction and anticipation of which patients in this cohort are most likely to have adverse outcomes. Biomarkers such as Galectin-3 (Gal-3), high sensitivity C-reactive protein (hsCRP) and N- Terminal-pro-B-type Natriuretic peptide (NT-proBNP) have proven useful in predicting outcomes in the vulnerable adult cardiac populations.


Benedicto A. Fernandes*1, David P. Bichell2, Mark A. Clay3

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